Artículos de referencia solo ofrece contenidos fiables que provienen...

  • de la pericia de nuestro Comité Científico, compuesto integralmente por neurólogos expertos en cefalea e internacionalmente reconocidos, tanto por su labor de investigación como su dedicación a pacientes.
  • de trabajos de investigación publicados en revistas especialistas referentes en cefalea y/o en investigación scientífica


En ocasiones menciona estudios o trabajos de investigación, o simplemente hace referencia a cifras publicadas en los mismos. Con el fin de garantizar transparencia, credibilidad y fiabilidad, se han referenciado los artículos fuente, que desglosamos a continuación:


1. Boehnke, C., Reuter, U., Flach, U., Schuh-Hofer, S., Einhäupl, K. M. and Arnold, G. (2004), High-dose riboflavin treatment is efficacious in migraine prophylaxis: an open study in a tertiary care centre. European Journal of Neurology, 11: 475–477.  (enlace) - doi: 10.1111/j.1468-1331.2004.00813.x 

2. Mauskop, A., & Altura, B. M. (1998). Role of magnesium in the pathogenesis and treatment of migraines. Clinical Neuroscience, 5(1), 24-27 (enlace)

3. Rozen, T., Oshinsky, M., Gebeline, C., Bradley, K., Young, W., Shechter, A. and Silberstein, S. (2002), Open label trial of coenzyme Q10 as a migraine preventive. Cephalalgia, 22: 137–141. (enlace) doi: 10.1046/j.1468-2982.2002.00335.x 

4. Rossi, P., Di Lorenzo, G., Malpezzi, M., Faroni, J., Cesarino, F., Di Lorenzo, C. and Nappi, G. (2005), Prevalence, pattern and predictors of use of complementary and alternative medicine (CAM) in migraine patients attending a headache clinic in Italy. Cephalalgia, 25: 493–506. (enlace) doi: 10.1111/j.1468-2982.2005.00898.x

5. Kaiser, J. What does a disease deserve? Science 20 November 2015: 350 (6263), 900-902. (enlace) doi: 10.1126/science.350.6263.900

6. Pietrobon D. Migraine: new molecular mechanisms. Neuroscientist. 2005;11(4):373-386

7. May A, Leone M. Update on cluster headache. Curr.Opin.Neurol. 2003;16(3):333-340.

8. Leone M, May A, Franzini A, et al. Deep brain stimulation for intractable chronic cluster headache: proposals for patient selection. Cephalalgia. 2004;24(11):934-937.

9. Oude Nijhuis JC, Haane DY, Koehler PJ. A review of the current and potential oxygen delivery systems and techniques utilized in cluster headache attacks. Cephalalgia. Nov 12 2015.

10. Bendtsen L. Central sensitization in tension-type headache--possible pathophysiological mechanisms. Cephalalgia. Jun 2000;20(5):486-508.

11. Rasmussen BK. Epidemiology of headache. Cephalalgia. 2001;21(7):774-777.

12. Steiner TJ, Stovner LJ, Katsarava Z, et al. The impact of headache in Europe: principal results of the Eurolight project. J Headache Pain. 2014;15:31.

13. Stovner L, Hagen K, Jensen R, et al. The global burden of headache: a documentation of headache prevalence and disability worldwide. Cephalalgia. Mar 2007;27(3):193-210.

14. Russell MB, Rasmussen BK, Fenger K, Olesen J. Migraine without aura and migraine with aura are distinct clinical entities: a study of four hundred and eighty-four male and female migraineurs from the general population [see comments]. Cephalalgia. 1996;16(4):239-245.

15. Pryse-Phillips WE, Dodick DW, Edmeads JG, et al. Guidelines for the diagnosis and management of migraine in clinical practice. Canadian Headache Society. CMAJ. May 1 1997;156(9):1273-1287.

16. Ophoff RA, Terwindt GM, Vergouwe MN, Frants RR, Ferrari MD. Wolff Award 1997. Involvement of a Ca2+ channel gene in familial hemiplegic migraine and migraine with and without aura. Dutch Migraine Genetics Research Group. Headache. 1997;37(8):479-485.

17. De Fusco M, Marconi R, Silvestri L, et al. Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2. Nat.Genet. 2003;33(2):192-196.

18. Dichgans M, Freilinger T, Eckstein G, et al. Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine. Lancet. 2005;366(9483):371-377.

19. Schwedt TJ. Chronic migraine. BMJ. 2014;348:g1416.

20. Scher AI, Stewart WF, Ricci JA, Lipton RB. Factors associated with the onset and remission of chronic daily headache in a population-based study. Pain. Nov 2003;106(1-2):81-89.

21. Schwartz BS, Stewart WF, Simon D, Lipton RB. Epidemiology of tension-type headache. JAMA. 1998;279(5):381-383.

22. Monteith TS, Sprenger T. Tension type headache in adolescence and childhood: where are we now? Curr Pain Headache Rep. Dec 2010;14(6):424-430.

23. Russell MB. Epidemiology and genetics of cluster headache. Lancet Neurol. 2004;3(5):279-283.

24. Mitsikostas DD, Edvinsson L, Jensen RH, et al. Refractory chronic cluster headache: a consensus statement on clinical definition from the European Headache Federation. J Headache Pain. 2014;15:79.

25. Pascual J, Iglesias F, Oterino A, Vazquez-Barquero A, Berciano J. Cough, exertional, and sexual headaches: an analysis of 72 benign and symptomatic cases. Neurology. Jun 1996;46(6):1520-1524.

26. D'Andrea G, Granella F, Verdelli F. Migraine with aura triggered by orgasm. Cephalalgia. Jul 2002;22(6):485-486.

27. Elias WJ, Burchiel KJ. Trigeminal neuralgia and other neuropathic pain syndromes of the head and face. Curr.Pain Headache Rep. 2002;6(2):115-124.

28. Giraud P, Valade D, Lanteri-Minet M, et al. Is migraine with cranial nerve palsy an ophthalmoplegic migraine? J Headache Pain. Apr 2007;8(2):119-122.

29. Schoenen J, Jacquy J, Lenaerts M. Effectiveness of high-dose riboflavin in migraine prophylaxis. A randomized controlled trial. Neurology. 1998;50(2):466-470.

30. Scher AI, Launer LJ. Migraine: migraine with aura increases the risk of stroke. Nat Rev Neurol. Mar 2010;6(3):128-129.

31. Kurth T, Diener HC. Current views of the risk of stroke for migraine with and migraine without aura. Curr Pain Headache Rep. Jun 2006;10(3):214-220.